BIO 538
Fall 2007
Instructor
Dr. Jacob P. Harney
Office: BC 160B
Phone: 768-5780
Email: harney@hartford.edu
Office Hours: MW 2:30-4 pm and by appointment
Time/Room MW: 4:20- 5:35, Dana 419
Laboratory M: 6:00-8:30 BC 166
Course Description
The fundamentals of neurophysiology are presented from the cellular to the systems levels. Preliminary discussion of the ionic and pharmacological basis of nerve and synaptic function serves as a foundation to subsequent discussion of the specialized neuronal geometries and synaptic circuitries associated with a variety of sensory, motor and central systems. The laboratory covers extracellular and intracellular techniques in neurorophysiology as well as brain sectioning, immunocytochemistry and critical examination of primary literature.
Text and Assignments
Kandel et al., Principles of Neural Science, 4th edition.
Most of the lecture is taken from the text, however, there will be material in lecture that may not be covered completely in the text. Handouts will be provided on occasion and outside reading may be assigned periodically. Read the chapters before the lectures!!
Laboratory
Laboratory responsibilities, expectations, grading and attendance policies will be discussed at your first laboratory session. Laboratory is an integral part of the course and will constitute 15% of your final class grade. Attendance is mandatory. The laboratory section of this course will be approximately 50% laboratory and 50% journal club format . Scientific papers related to current topics in the course will be assigned and presented by students for the purposes of learning how to read and critique the scientific literature. In addition, these will be used to teach methodologies that cannot be done completely or effectively in a laboratory that meets only one night a week.
Independent Report
Each student will research a clinical or basic application of neurophysiology. This project will be discussed in more detail in class. A final report will be submitted be each student in the form of a PowerPoint presentation which will be presented briefly to the rest of the class during the last lab session of the semester. The presentation will constitute 10% of your final grade.
Examination and Grading Policy
Examinations will consist of two 90 minute examinations during the course, each worth 25% of your final grade. In addition, there will be a comprehensive final examination which will also constitute 25% of your final grade. Exams will be admixtures of multiple choice, true/false, short answer and problems (where appropriate) questions. There will be no makeup exams.
Final Course Grade
Lecture grade: 75%
Laboratory grade: 15%
Independent report: 10%
Letter grades will be determined at the end of the course as follows:
A > 90%, B > 80%, C > 70%, D > 60%, F< 60%
_______Syllabus: Principles of Neurophysiology / BIO 538 / Fall 2007
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Neuroscience Tutorial |
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Ch 3,4 | ||
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| Nobel Prize/Neuroscience |
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Chap 7, Appen A
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Chap 13
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Chap 14 | |||
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Chap 16 | |||
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