LOIS
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Lois Griffin (née Pewterschmidt) is a fictional character in the animated comedy series Family Guy, the matriarch of the Griffin family. She is voiced by writer Alex Borstein and first appeared on television, along with the rest of the family in the 15-minute short on December 20, 1998. Lois was created and designed by series creator Seth MacFarlane. MacFarlane was asked to pitch a pilot to the Fox Broadcasting Company based on Larry and Steve, a short made by MacFarlane which featured a middle-aged character named Larry and an intellectual dog, Steve. After the pilot was given the green light, The Griffin family appeared on the episode "Death Has a Shadow".

Lois is the mother of the Griffin family. With her husband Peter, she has had three children: Meg, Chris, and Stewie. Lois is often portrayed as a stereotypical television mother, despite her admitted drug use, meth addiction, prior gambling addiction and obvious kleptomania. She has appeared in other media relating to Family Guy—including a video game, commercials and books—and inspired an entire line of merchandise.

Lois's distinctive New York accent originated from a character in a stage show that Alex Borstein had performed in, which was largely inspired by a relative who grew up in Long Island, New York.

Lois Griffin is a Protestant with a Long Island and New York accent. She's the wife of Peter Griffin and the mother of Meg, Chris and Stewie Griffin. She is the daughter of Carter and Barbara Pewterschmidt. Lois and the rest of the Griffins live in the fictional town of Quahog, Rhode Island which is modeled after Cranston, Rhode Island.[1][2][3] Lois primarily works as a housewife throughout the series, though she did give piano lessons in early episodes of the series. Lois has also had various jobs in single episodes such as in "FOX-y Lady", (season 7, 2009) were she becomes the new reporter for FOX News and in "It Takes a Village Idiot, and I Married One", (season 5, 2007) Lois is elected the mayor of Quahog.

Family Guy uses a floating timeline in which the characters do not age much, so the show is always assumed to be set in the current year. However, several of the characters, such as Meg Griffin, have aged two to three years since the show's pilot episode, while others, such as Stewie and Brian, have remained the same age.[4] In several episodes, events have been linked to specific times, although this timeline has been contradicted in subsequent episodes.

(http://en.wikipedia.org/wiki/Lois_Griffin)