| Substance | Observed Effects |
| Nicotine - one or more packs of cigarettes per day | Low birth weight
Hyperactivity |
| Cocaine | Exposure when an embryo may
result in mental retardation
Exposure when a fetus may result in hyperactivity, motor problems |
| Alcohol | 1-2 drinks/day:
|
| Lead in environment | Memory problems, low verbal intelligence |
| Herpes | Brain damage, miscarriage (if birth canal is infected) |